GrippeEspagneV1, Main, Exploration, bibRecord, 000254

Influenza vaccine effectiveness in preventing outpatient, inpatient, and severe cases of laboratory-confirmed influenza.

Identifieur interne : 000254 ( Main/Exploration ); précédent : 000253; suivant : 000255

Influenza vaccine effectiveness in preventing outpatient, inpatient, and severe cases of laboratory-confirmed influenza.

Auteurs : Jesús Castilla [Espagne] ; Pere Godoy ; Angela Domínguez ; Iván Martínez-Baz ; Jenaro Astray ; Vicente Martín ; Miguel Delgado-Rodríguez ; Maretva Baricot ; Nuria Soldevila ; José María Mayoral ; José María Quintana ; Juan Carlos Galán ; Ady Castro ; Fernando González-Candelas ; Olatz Garín ; Marc Saez ; Sonia Tamames ; Tomás Pumarola

Source :

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2013.

RBID : pubmed:23532475

Descripteurs français

KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Enfant (MeSH), Enfant d'âge préscolaire (MeSH), Espagne (épidémiologie), Femelle (MeSH), Grippe humaine (anatomopathologie), Grippe humaine (diagnostic), Grippe humaine (prévention et contrôle), Grippe humaine (épidémiologie), Grossesse (MeSH), Hospitalisation (statistiques et données numériques), Humains (MeSH), Infection croisée (anatomopathologie), Infection croisée (diagnostic), Infection croisée (prévention et contrôle), Infection croisée (épidémiologie), Infections communautaires (anatomopathologie), Infections communautaires (diagnostic), Infections communautaires (prévention et contrôle), Infections communautaires (épidémiologie), Jeune adulte (MeSH), Mâle (MeSH), Nourrisson (MeSH), Nouveau-né (MeSH), Patients en consultation externe (MeSH), Patients hospitalisés (MeSH), Pronostic (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Vaccins antigrippaux (administration et posologie), Vaccins antigrippaux (immunologie), Études cas-témoins (MeSH).
MESH :
- administration et posologie : Vaccins antigrippaux.
- anatomopathologie : Grippe humaine, Infection croisée, Infections communautaires.
- diagnostic : Grippe humaine, Infection croisée, Infections communautaires.
- immunologie : Vaccins antigrippaux.
- prévention et contrôle : Grippe humaine, Infection croisée, Infections communautaires.
- statistiques et données numériques : Hospitalisation.
- épidémiologie : Espagne, Grippe humaine, Infection croisée, Infections communautaires.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Femelle, Grossesse, Humains, Jeune adulte, Mâle, Nourrisson, Nouveau-né, Patients en consultation externe, Patients hospitalisés, Pronostic, Sujet âgé, Sujet âgé de 80 ans ou plus, Études cas-témoins.
Wicri :
- geographic : Espagne.

English descriptors

KwdEn :
- Adolescent (MeSH), Adult (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Case-Control Studies (MeSH), Child (MeSH), Child, Preschool (MeSH), Community-Acquired Infections (diagnosis), Community-Acquired Infections (epidemiology), Community-Acquired Infections (pathology), Community-Acquired Infections (prevention & control), Cross Infection (diagnosis), Cross Infection (epidemiology), Cross Infection (pathology), Cross Infection (prevention & control), Female (MeSH), Hospitalization (statistics & numerical data), Humans (MeSH), Infant (MeSH), Infant, Newborn (MeSH), Influenza Vaccines (administration & dosage), Influenza Vaccines (immunology), Influenza, Human (diagnosis), Influenza, Human (epidemiology), Influenza, Human (pathology), Influenza, Human (prevention & control), Inpatients (MeSH), Male (MeSH), Middle Aged (MeSH), Outpatients (MeSH), Pregnancy (MeSH), Prognosis (MeSH), Spain (epidemiology), Young Adult (MeSH).
MESH :
- chemical , administration & dosage : Influenza Vaccines.
- geographic , epidemiology : Spain.
- diagnosis : Community-Acquired Infections, Cross Infection, Influenza, Human.
- epidemiology : Community-Acquired Infections, Cross Infection, Influenza, Human.
- chemical , immunology : Influenza Vaccines.
- pathology : Community-Acquired Infections, Cross Infection, Influenza, Human.
- prevention & control : Community-Acquired Infections, Cross Infection, Influenza, Human.
- statistics & numerical data : Hospitalization.
- Adolescent, Adult, Aged, Aged, 80 and over, Case-Control Studies, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Inpatients, Male, Middle Aged, Outpatients, Pregnancy, Prognosis, Young Adult.

Abstract

BACKGROUND

In most seasons, the influenza vaccine is effective in preventing influenza, but it is not clear whether it is equally effective in preventing mild and severe cases. We designed a case-control study to compare the effectiveness of the influenza vaccine in preventing outpatient, inpatient, and severe or fatal cases of laboratory-confirmed influenza.

METHODS

Hospitalized patients (n = 691) with laboratory-confirmed influenza in the 2010-2011 season recruited in 29 Spanish hospitals were individually matched by age, admission/visit date, and province with an outpatient with laboratory-confirmed influenza and an outpatient control. Severe cases were considered those patients admitted to intensive care units or who died in the hospital (n = 177). We compared the influenza vaccine status of controls and outpatient cases, inpatient cases, and severe cases using conditional logistic regression adjusted for potential confounding factors. Severe and nonsevere inpatient influenza cases were compared using unconditional logistic regression. Vaccine effectiveness was (1 - odds ratio) × 100.

RESULTS

Vaccine effectiveness was 75% (adjusted odds ratio [AOR], 0.25; 95% confidence interval [CI], .16-.39) in preventing influenza outpatient cases, 60% (AOR, 0.40; 95% CI, .25-.63) in preventing influenza-associated hospitalizations, and 89% (AOR, 0.11; 95% CI, .04-.37) in preventing severe cases. In inpatients, influenza vaccination was associated with a lower risk of severe influenza (AOR, 0.42; 95% CI, .22-.80).

CONCLUSIONS

Influenza vaccination prevented influenza cases and hospitalizations and was associated with a better prognosis in inpatients with influenza. The combined effect of these 2 mechanisms would explain the high effectiveness of the vaccine in preventing severe cases due to influenza.

DOI: 10.1093/cid/cit194
PubMed: 23532475

Affiliations:

Espagne

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 00252
to stream Main, to step Curation: 000252

Le document en format XML

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<term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Case-Control Studies (MeSH)</term>
<term>Child (MeSH)</term>
<term>Child, Preschool (MeSH)</term>
<term>Community-Acquired Infections (diagnosis)</term>
<term>Community-Acquired Infections (epidemiology)</term>
<term>Community-Acquired Infections (pathology)</term>
<term>Community-Acquired Infections (prevention & control)</term>
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<term>Cross Infection (epidemiology)</term>
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<term>Influenza Vaccines (immunology)</term>
<term>Influenza, Human (diagnosis)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (pathology)</term>
<term>Influenza, Human (prevention & control)</term>
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<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
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<term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Enfant (MeSH)</term>
<term>Enfant d'âge préscolaire (MeSH)</term>
<term>Espagne (épidémiologie)</term>
<term>Femelle (MeSH)</term>
<term>Grippe humaine (anatomopathologie)</term>
<term>Grippe humaine (diagnostic)</term>
<term>Grippe humaine (prévention et contrôle)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Grossesse (MeSH)</term>
<term>Hospitalisation (statistiques et données numériques)</term>
<term>Humains (MeSH)</term>
<term>Infection croisée (anatomopathologie)</term>
<term>Infection croisée (diagnostic)</term>
<term>Infection croisée (prévention et contrôle)</term>
<term>Infection croisée (épidémiologie)</term>
<term>Infections communautaires (anatomopathologie)</term>
<term>Infections communautaires (diagnostic)</term>
<term>Infections communautaires (prévention et contrôle)</term>
<term>Infections communautaires (épidémiologie)</term>
<term>Jeune adulte (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Nourrisson (MeSH)</term>
<term>Nouveau-né (MeSH)</term>
<term>Patients en consultation externe (MeSH)</term>
<term>Patients hospitalisés (MeSH)</term>
<term>Pronostic (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Sujet âgé de 80 ans ou plus (MeSH)</term>
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<term>Vaccins antigrippaux (immunologie)</term>
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<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Grippe humaine</term>
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<term>Infections communautaires</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Community-Acquired Infections</term>
<term>Cross Infection</term>
<term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Community-Acquired Infections</term>
<term>Cross Infection</term>
<term>Influenza, Human</term>
</keywords>
<keywords scheme="MESH" qualifier="prévention et contrôle" xml:lang="fr"><term>Grippe humaine</term>
<term>Infection croisée</term>
<term>Infections communautaires</term>
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<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term>
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<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Espagne</term>
<term>Grippe humaine</term>
<term>Infection croisée</term>
<term>Infections communautaires</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Case-Control Studies</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Infant, Newborn</term>
<term>Inpatients</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Outpatients</term>
<term>Pregnancy</term>
<term>Prognosis</term>
<term>Young Adult</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Enfant</term>
<term>Enfant d'âge préscolaire</term>
<term>Femelle</term>
<term>Grossesse</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Nouveau-né</term>
<term>Patients en consultation externe</term>
<term>Patients hospitalisés</term>
<term>Pronostic</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Études cas-témoins</term>
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<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>In most seasons, the influenza vaccine is effective in preventing influenza, but it is not clear whether it is equally effective in preventing mild and severe cases. We designed a case-control study to compare the effectiveness of the influenza vaccine in preventing outpatient, inpatient, and severe or fatal cases of laboratory-confirmed influenza.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>Hospitalized patients (n = 691) with laboratory-confirmed influenza in the 2010-2011 season recruited in 29 Spanish hospitals were individually matched by age, admission/visit date, and province with an outpatient with laboratory-confirmed influenza and an outpatient control. Severe cases were considered those patients admitted to intensive care units or who died in the hospital (n = 177). We compared the influenza vaccine status of controls and outpatient cases, inpatient cases, and severe cases using conditional logistic regression adjusted for potential confounding factors. Severe and nonsevere inpatient influenza cases were compared using unconditional logistic regression. Vaccine effectiveness was (1 - odds ratio) × 100.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>Vaccine effectiveness was 75% (adjusted odds ratio [AOR], 0.25; 95% confidence interval [CI], .16-.39) in preventing influenza outpatient cases, 60% (AOR, 0.40; 95% CI, .25-.63) in preventing influenza-associated hospitalizations, and 89% (AOR, 0.11; 95% CI, .04-.37) in preventing severe cases. In inpatients, influenza vaccination was associated with a lower risk of severe influenza (AOR, 0.42; 95% CI, .22-.80).</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>Influenza vaccination prevented influenza cases and hospitalizations and was associated with a better prognosis in inpatients with influenza. The combined effect of these 2 mechanisms would explain the high effectiveness of the vaccine in preventing severe cases due to influenza.</p>
</div>
</front>
</TEI>
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<Title>Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</Title>
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<ArticleTitle>Influenza vaccine effectiveness in preventing outpatient, inpatient, and severe cases of laboratory-confirmed influenza.</ArticleTitle>
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<ELocationID EIdType="doi" ValidYN="Y">10.1093/cid/cit194</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">In most seasons, the influenza vaccine is effective in preventing influenza, but it is not clear whether it is equally effective in preventing mild and severe cases. We designed a case-control study to compare the effectiveness of the influenza vaccine in preventing outpatient, inpatient, and severe or fatal cases of laboratory-confirmed influenza.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Hospitalized patients (n = 691) with laboratory-confirmed influenza in the 2010-2011 season recruited in 29 Spanish hospitals were individually matched by age, admission/visit date, and province with an outpatient with laboratory-confirmed influenza and an outpatient control. Severe cases were considered those patients admitted to intensive care units or who died in the hospital (n = 177). We compared the influenza vaccine status of controls and outpatient cases, inpatient cases, and severe cases using conditional logistic regression adjusted for potential confounding factors. Severe and nonsevere inpatient influenza cases were compared using unconditional logistic regression. Vaccine effectiveness was (1 - odds ratio) × 100.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Vaccine effectiveness was 75% (adjusted odds ratio [AOR], 0.25; 95% confidence interval [CI], .16-.39) in preventing influenza outpatient cases, 60% (AOR, 0.40; 95% CI, .25-.63) in preventing influenza-associated hospitalizations, and 89% (AOR, 0.11; 95% CI, .04-.37) in preventing severe cases. In inpatients, influenza vaccination was associated with a lower risk of severe influenza (AOR, 0.42; 95% CI, .22-.80).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Influenza vaccination prevented influenza cases and hospitalizations and was associated with a better prognosis in inpatients with influenza. The combined effect of these 2 mechanisms would explain the high effectiveness of the vaccine in preventing severe cases due to influenza.</AbstractText>
</Abstract>
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<ForeName>Jesús</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Instituto de Salud Pública de Navarra, Pamplona, Spain. jcastilc@navarra.es</Affiliation>
</AffiliationInfo>
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<ForeName>Pere</ForeName>
<Initials>P</Initials>
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<ForeName>Angela</ForeName>
<Initials>A</Initials>
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<ForeName>Iván</ForeName>
<Initials>I</Initials>
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<ForeName>Jenaro</ForeName>
<Initials>J</Initials>
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<ForeName>Vicente</ForeName>
<Initials>V</Initials>
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<ForeName>Miguel</ForeName>
<Initials>M</Initials>
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<ForeName>Maretva</ForeName>
<Initials>M</Initials>
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<Initials>N</Initials>
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<ForeName>José María</ForeName>
<Initials>JM</Initials>
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<ForeName>José María</ForeName>
<Initials>JM</Initials>
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<Initials>JC</Initials>
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<ForeName>Ady</ForeName>
<Initials>A</Initials>
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<ForeName>Fernando</ForeName>
<Initials>F</Initials>
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<Initials>O</Initials>
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<ForeName>Marc</ForeName>
<Initials>M</Initials>
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<ForeName>Sonia</ForeName>
<Initials>S</Initials>
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<ForeName>Tomás</ForeName>
<Initials>T</Initials>
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<Language>eng</Language>
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<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
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<Month>03</Month>
<Day>26</Day>
</ArticleDate>
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<MedlineTA>Clin Infect Dis</MedlineTA>
<NlmUniqueID>9203213</NlmUniqueID>
<ISSNLinking>1058-4838</ISSNLinking>
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<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D007252">Influenza Vaccines</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
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<Keyword MajorTopicYN="N">vaccine effectiveness</Keyword>
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<name sortKey="Galan, Juan Carlos" sort="Galan, Juan Carlos" uniqKey="Galan J" first="Juan Carlos" last="Galán">Juan Carlos Galán</name>
<name sortKey="Garin, Olatz" sort="Garin, Olatz" uniqKey="Garin O" first="Olatz" last="Garín">Olatz Garín</name>
<name sortKey="Godoy, Pere" sort="Godoy, Pere" uniqKey="Godoy P" first="Pere" last="Godoy">Pere Godoy</name>
<name sortKey="Gonzalez Candelas, Fernando" sort="Gonzalez Candelas, Fernando" uniqKey="Gonzalez Candelas F" first="Fernando" last="González-Candelas">Fernando González-Candelas</name>
<name sortKey="Martin, Vicente" sort="Martin, Vicente" uniqKey="Martin V" first="Vicente" last="Martín">Vicente Martín</name>
<name sortKey="Martinez Baz, Ivan" sort="Martinez Baz, Ivan" uniqKey="Martinez Baz I" first="Iván" last="Martínez-Baz">Iván Martínez-Baz</name>
<name sortKey="Mayoral, Jose Maria" sort="Mayoral, Jose Maria" uniqKey="Mayoral J" first="José María" last="Mayoral">José María Mayoral</name>
<name sortKey="Pumarola, Tomas" sort="Pumarola, Tomas" uniqKey="Pumarola T" first="Tomás" last="Pumarola">Tomás Pumarola</name>
<name sortKey="Quintana, Jose Maria" sort="Quintana, Jose Maria" uniqKey="Quintana J" first="José María" last="Quintana">José María Quintana</name>
<name sortKey="Saez, Marc" sort="Saez, Marc" uniqKey="Saez M" first="Marc" last="Saez">Marc Saez</name>
<name sortKey="Soldevila, Nuria" sort="Soldevila, Nuria" uniqKey="Soldevila N" first="Nuria" last="Soldevila">Nuria Soldevila</name>
<name sortKey="Tamames, Sonia" sort="Tamames, Sonia" uniqKey="Tamames S" first="Sonia" last="Tamames">Sonia Tamames</name>
</noCountry>
<country name="Espagne"><noRegion><name sortKey="Castilla, Jesus" sort="Castilla, Jesus" uniqKey="Castilla J" first="Jesús" last="Castilla">Jesús Castilla</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/GrippeEspagneV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000254 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000254 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    GrippeEspagneV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:23532475
   |texte=   Influenza vaccine effectiveness in preventing outpatient, inpatient, and severe cases of laboratory-confirmed influenza.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:23532475" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a GrippeEspagneV1

This area was generated with Dilib version V0.6.37.
Data generation: Fri Sep 25 11:01:38 2020. Site generation: Sat Feb 13 17:38:04 2021

	Serveur d'exploration sur la grippe en Espagne
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Serveur d'exploration sur la grippe en Espagne

Influenza vaccine effectiveness in preventing outpatient, inpatient, and severe cases of laboratory-confirmed influenza.

Influenza vaccine effectiveness in preventing outpatient, inpatient, and severe cases of laboratory-confirmed influenza.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

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Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki